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Objective: To determine the prevalence of sleep apnea (SA) during the first night after hemispheric ischemic stroke and its influence on clinical presentation, course, and functional outcome at 6 months.

Methods: The first night after cerebral infarction onset, 50 patients underwent polysomnography (PSG) followed by oximetry during the next 24 hours. Neurologic severity and early worsening were assessed by the Scandinavian Stroke Scale and outcome by the Barthel Index. Patients were evaluated on admission, on the third day, at discharge, and at 1, 3, and 6 months.

Results: There were 30 males and 20 females with a mean age of 66.8 ± 9.5 years. Latency between stroke onset and PSG was 11.6 ± 5.3 hours. Thirty-one (62%) subjects had SA (apnea–hypopnea index [AHI] ≥ 10). Of these, 23 (46%) had an AHI ≥20 and 21 (42%) an AHI ≥25. Sleep-related stroke onset occurred in 24 (48%) patients …