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We determined the isotropic indentation modulus of precipitates in cubic materials by using the indentation modulus of the matrix as a reference. This eliminates major practical difficulty of repeatedly switching between a sample and a reference for measurement of indentation modulus using atomic force acoustic microscopy. The methodology has been demonstrated for mapping the elastic stiffness of∼ 500 nm sized M 23 C 6 precipitates in alloy 625 and ferritic steel with a spatial resolution of∼ 50 nm⁠.