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We conducted a prospective clinical trial of transoral robotic surgery in patients with hypopharyngeal cancer and herein report the long-term oncological and functional outcomes.

Between April 2008 and March 2014, 45 patients diagnosed with hypopharyngeal cancer participated in this prospective study.

All patients were male with a mean age of 66.7 years. The median follow-up period was 60 months. Patients were classified using the staging system of the American Joint Commission on Cancer, as follows: Stage I, 7.9%; Stage II, 5.3%; Stage III, 15.8%; Stage IV, 71.1. Of all 38 patients, 17 (44.7%) were alive with no evidence of disease at the last follow-up. Seven patients (18.4%) died of TNM-related disease and fourteen (36.8%) from other causes. The 5-year disease-specific survival rate of stage I and II patients was 100.0%, and that of stage III and IV patients was 74.0 …