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Breast cancer positions as the most well-known threat and the main source of malignant growth-related morbidity and mortality throughout the world. It is apical of all new cancer incidences analyzed among females. However, machine learning algorithms have given rise to progress across different domains. There are various diagnostic methods available for cancer detection. However, cancer detection through histopathological images is considered to be more accurate. In this research, we have proposed the Stacked Generalized Ensemble (SGE) approach for breast cancer classification into Invasive Ductal Carcinoma+ and Invasive Ductal Carcinoma-. SGE is inspired by the stacking model which utilizes output predictions. Here, SGE uses six deep learning models as level-0 learner models or sub-models and Logistic regression is used as Level–1 learner or meta–learner model. Invasive Ductal Carcinoma …