作者
Veronica Frewer, Courtney P Gilchrist, Simonne E Collins, Katrina Williams, Marc L Seal, Richard J Leventer, David J Amor
发表日期
2021/11
来源
Journal of Child Psychology and Psychiatry
卷号
62
期号
11
页码范围
1339-1352
简介
Background
Research on monogenic forms of autism spectrum disorder (autism) can inform our understanding of genetic contributions to the autism phenotype; yet, there is much to be learned about the pathways from gene to brain structure to behavior. This systematic review summarizes and evaluates research on brain magnetic resonance imaging (MRI) findings in monogenic conditions that have strong association with autism. This will improve understanding of the impact of genetic variability on brain structure and related behavioral traits in autism.
Methods
The search strategy for this systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. Risk of bias (ROB) assessment was completed on included studies using the Newcastle‐Ottawa Scales.
Results
Of 4,287 studies screened, 69 were included pertaining to 13 of the top 20 genes with the strongest …
学术搜索中的文章
V Frewer, CP Gilchrist, SE Collins, K Williams, ML Seal… - Journal of Child Psychology and Psychiatry, 2021