作者
Valentina Borghesani, Cheng Wang, Christa Watson, Florence Bouhali, Eduardo Caverzasi, Giovanni Battistella, Rian Bogley, Nicole A Yabut, Jessica Deleon, Zachary A Miller, Fumiko Hoeft, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini
发表日期
2021/9
期刊
Journal of Neuroimaging
卷号
31
期号
5
页码范围
962-972
简介
Background and Purpose
The ventral occipitotemporal cortex (vOT) is a region crucial for reading acquisition through selective tuning to printed words. Developmental dyslexia is a disorder of reading with underlying neurobiological bases often associated with atypical neural responses to printed words. Previous studies have discovered anomalous structural development and function of the vOT in individuals with dyslexia. However, it remains unclear if or how structural abnormalities relate to functional alterations.
Methods
In this study, we acquired structural, functional (words and faces processing), and diffusion MRI data from 26 children with dyslexia (average age = 10.4 ± 2.0 years) and 14 age‐matched typically developing readers (average age = 10.4 ± 1.6 years). Morphological indices of local gyrification, neurite density (i.e., dendritic arborization structure), and orientation dispersion (i.e., dendritic …
引用总数
2021202220232024135