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To evaluate the feasibility of a simultaneous single scan of regional krypton and iodine concentrations by using dual-energy computed tomography (CT).

The study was approved by the institutional animal experimental committee. An airway obstruction model was first made in 10 beagle dogs, and a pulmonary arterial occlusion was induced in each animal after 1 week. For each model, three sessions of dual-energy CT (80% krypton ventilation [krypton CT], 80% krypton ventilation with iodine enhancement [mixed–contrast agent CT], and iodine enhancement [iodine CT]) were performed. Krypton maps were made from krypton and mixed–contrast agent CT, and iodine maps were made from iodine and mixed–contrast …