作者
Claudia Hopenhayn, Amy Christian, Warren Jay Christian, Meg Watson, Elizabeth R Unger, Charles F Lynch, Edward S Peters, Edward J Wilkinson, Youjie Huang, Glenn Copeland, Wendy Cozen, Maria Sibug Saber, Marc T Goodman, Brenda Y Hernandez, Martin Steinau, Christopher Lyu, Thomas T Tucker, Mona Saraiya
发表日期
2014/4/1
期刊
Journal of lower genital tract disease
卷号
18
期号
2
页码范围
182-189
出版商
LWW
简介
Objective We conducted a baseline study of human papillomavirus (HPV) type prevalence in invasive cervical cancers (ICCs) using data from 7 cancer registries (CRs) in the United States. Cases were diagnosed between 1994 and 2005 before the implementation of the HPV vaccines.
Materials and Methods Cancer registries from Florida, Kentucky, Louisiana, Michigan, Hawaii, Iowa, and Los Angeles, California identified eligible ICC cases and obtained sections from representative blocks of archived tumor specimens for DNA extraction. All extracts were assayed by linear array and, if inadequate or HPV negative, retested with INNO-LiPA Genotype test. Clinical and demographic factors were obtained from the CRs and merged with the HPV typing data to analyze factors associated with different types and with HPV negativity.
Results A total of 777 ICCs were included in this analysis, with broad geographic, age, and …
学术搜索中的文章
C Hopenhayn, A Christian, WJ Christian, M Watson… - Journal of lower genital tract disease, 2014