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In present day’s global competitive environment, enterprises have to focus on their supply chain performance to have a competitive advantage. Improving the effectiveness of the system is the only way to do so and, for this purpose, ongoing supply chain activities have to be inspected in pursuant of some performance measurements and metrics to cover the concept. There is a lack of effective mathematical models in the literature which enclose flexibility and its parameters in order to measure the performance of a supply chain by considering all of its vital elements. In this paper, a mathematical model is proposed to evaluate supply chain performance using some key performance indicators. This model can be used to evaluate the flexibility characteristics of logistic, market, supplier, machine, labor, information system, and routing of the supply chain.