作者
Manasi Agrawal, Mark Aleynick, Meriem Belabed, Graham Britton, Matthew Brown, Maria Casanova-Acebes, Jovani Catalan, Monica Centa, Andrew Charap, Andrew Chan, Steven Chen, Jonathan Chung, Cansu Cimen Bozkus, Evan Cody, Francesca Cossarini, Erica Dalla, Nicolas Fernandez, John Grout, Conor Gruber, Dan Fu Ruan, Pauline Hamon, Samarth Hegde, Etienne Humblin, Divya Jha, Maria Kuksin, Julia Kodysh, Andrew Leader, Rachel Levantovsky, Matthew Lin, Katherine Lindblad, Daniel Lozano-Ojalvo, Gabrielle Lubitz, Assaf Magen, Zafar Mahmood, Louise Malle, Gustavo Martinez-Delgado, Jaime Mateus-Tique, Elliot Meritt, Chang Moon, Alvaro Moreira, Justine Noel, Tim O’Donnell, Miyo Ota, Matthew D Park, Luisanna Pia, Tamar Plitt, Venu Pothula, Jamie Redes, Ivan Reyes Torres, Emma Risson, Mark Roberto, Alfonso Rodriguez, Miriam Saffern, Bérengère Salomé, Myvizhi Esai Selvan, Joan Shang, Matthew Spindler, Alessandra Soares Schanoski, Maria Suprun, Jessica Tan, Michelle Tran, Verena van der Heide, Natalie Vaninov, C Matthias Wilk, Julio Aguirre-Ghiso, Konstantina Alexandropoulos, Nina Bhardwaj, Dusan Bogunovic, Brian Brown, Judy Cho, Jeremiah Faith, Emilie Grasset, Zeynep H Gümüş, Peter Heeger, Dirk Homann, Amir Horowitz, Ephraim Kenigsberg, Alice O Kamphorst, Florian Krammer, Maria A Curotto de Lafaille, Uri Laserson
发表日期
2020
简介
The coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biological underpinning of COVID19 pathophysiology. In this review, we summarize the current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death. We also discuss the rationale and clinical outcome of current therapeutic strategies as well as prospective clinical trials to prevent or treat SARS-CoV-2 infection.
学术搜索中的文章
M Agrawal, M Aleynick, M Belabed, G Britton, M Brown… - 2020