作者
Nicolas Vabret, Graham J Britton, Conor Gruber, Samarth Hegde, Joel Kim, Maria Kuksin, Rachel Levantovsky, Louise Malle, Alvaro Moreira, Matthew D Park, Luisanna Pia, Emma Risson, Miriam Saffern, Bérengère Salomé, Myvizhi Esai Selvan, Matthew P Spindler, Jessica Tan, Verena van Der Heide, Jill K Gregory, Konstantina Alexandropoulos, Nina Bhardwaj, Brian D Brown, Benjamin Greenbaum, Zeynep H Gümüş, Dirk Homann, Amir Horowitz, Alice O Kamphorst, Maria A Curotto de Lafaille, Saurabh Mehandru, Miriam Merad, Robert M Samstein, Manasi Agrawal, Mark Aleynick, Meriem Belabed, Matthew Brown, Maria Casanova-Acebes, Jovani Catalan, Monica Centa, Andrew Charap, Andrew Chan, Steven T Chen, Jonathan Chung, Cansu Cimen Bozkus, Evan Cody, Francesca Cossarini, Erica Dalla, Nicolas Fernandez, John Grout, Dan Fu Ruan, Pauline Hamon, Etienne Humblin, Divya Jha, Julia Kodysh, Andrew Leader, Matthew Lin, Katherine Lindblad, Daniel Lozano-Ojalvo, Gabrielle Lubitz, Assaf Magen, Zafar Mahmood, Gustavo Martinez-Delgado, Jaime Mateus-Tique, Elliot Meritt, Chang Moon, Justine Noel, Tim O’Donnell, Miyo Ota, Tamar Plitt, Venu Pothula, Jamie Redes, Ivan Reyes Torres, Mark Roberto, Alfonso R Sanchez-Paulete, Joan Shang, Alessandra Soares Schanoski, Maria Suprun, Michelle Tran, Natalie Vaninov, C Matthias Wilk, Julio Aguirre-Ghiso, Dusan Bogunovic, Judy Cho, Jeremiah Faith, Emilie Grasset, Peter Heeger, Ephraim Kenigsberg, Florian Krammer, Uri Laserson
发表日期
2020/6/16
来源
Immunity
卷号
52
期号
6
页码范围
910-941
出版商
Elsevier
简介
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biological underpinning of COVID19 pathophysiology. In this Review, we summarize the current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death. We also discuss the rationale and clinical outcome of current therapeutic strategies as well as prospective clinical trials to prevent or treat SARS-CoV-2 infection.
学术搜索中的文章
N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020