作者
Samu Kainulainen, Juha Töyräs, Arie Oksenberg, Henri Korkalainen, Sandra Sefa, Antti Kulkas, Timo Leppänen
发表日期
2019/8/15
期刊
Journal of Clinical Sleep Medicine
卷号
15
期号
8
页码范围
1135-1142
出版商
American Academy of Sleep Medicine
简介
Study Objectives
The aim was to investigate how the severity of apneas, hypopneas, and related desaturations is associated with obstructive sleep apnea (OSA)-related daytime sleepiness.
Methods
Multiple Sleep Latency Tests and polysomnographic recordings of 362 patients with OSA were retrospectively analyzed and novel diagnostic parameters (eg, obstruction severity and desaturation severity), incorporating severity of apneas, hypopneas, and desaturations, were computed. Conventional statistical analysis and multivariate analyses were utilized to investigate connection of apnea-hypopnea index (AHI), oxygen desaturation index (ODI), conventional hypoxemia parameters, and novel diagnostic parameters with mean daytime sleep latency (MSL).
Results
In the whole population, 10% increase in values of desaturation severity (risk ratio = 2.01, P < .001), obstruction severity (risk ratio = 2.18, P < .001) and time …
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