作者
Rosa A Hoekstra, Meike Bartels, Catharina JH Verweij, Dorret I Boomsma
发表日期
2007/4/1
期刊
Archives of Pediatrics and Adolescent Medicine
卷号
161
期号
4
页码范围
372
出版商
JAMA
简介
Objective
To explore genetic and environmental influences on individual differences in autistic traits in early adulthood and to test if there is assortative mating (nonrandom partner choice) for autistic traits in the general population.
Design
Twin family study using structural equation modeling.
Setting
Population-based twin family sample from the Netherlands.
Participants
Twins aged 18 years (n = 370) and their siblings (n = 94); parents of twins (128 couples).
Main Outcome Measure
Self-reported Autism-Spectrum Quotient (AQ) scores, a quantitative measure of autistic traits.
Results
Autistic traits were continuously distributed in the population. Twins and siblings did not significantly differ in AQ scores; men obtained significantly higher AQ scores than women (in twin-sibling sample,P<.001; twin-parent sample,P = .02). Individual differences in endorsement on autistic traits show substantial heritability (57%). No significant …
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RA Hoekstra, M Bartels, CJH Verweij, DI Boomsma - Archives of pediatrics & adolescent medicine, 2007