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Background

Sevoflurane is commonly used as an inhalational induction agent in paediatric patients. Emergence agitation is a common post-operative problem in young children who have received sevoflurane. Clonidine has proven to be effective in reducing the incidence of post-operative agitation at a higher dose (3 and 2 μg kg− 1). It has some dose-dependent disadvantages, prominently bradycardia, hypotension and respiratory impairment.

Objective

The authors conducted a study to evaluate the effectiveness of low-dose caudal clonidine (1 μg kg− 1) in reducing the incidence of sevoflurane-induced agitation in preschool children undergoing urogenital and lower limb surgery.