作者
Marcello Covino, Antonio De Vita, Alessia d'Aiello, Salvatore Emanuele Ravenna, Aureliano Ruggio, Lorenzo Genuardi, Benedetta Simeoni, Andrea Piccioni, Giuseppe De Matteis, Rita Murri, Antonio Maria Leone, Andrea Flex, Antonio Gasbarrini, Giovanna Liuzzo, Massimo Massetti, Francesco Franceschi
发表日期
2023/5/2
期刊
Journal of the American Heart Association
卷号
12
期号
9
页码范围
e027650
简介
Background
Infective endocarditis (IE) could be suspected in any febrile patients admitted to the emergency department (ED). This study was aimed at assessing clinical criteria predictive of IE and identifying and prospectively validating a sensible and easy‐to‐use clinical prediction score for the diagnosis of IE in the ED.
Methods and Results
We conducted a retrospective observational study, enrolling consecutive patients with fever admitted to the ED between January 2015 and December 2019 and subsequently hospitalized. Several clinical and anamnestic standardized variables were collected and evaluated for the association with IE diagnosis. We derived a multivariate prediction model by logistic regression analysis. The identified predictors were assigned a score point value to obtain the Clinical Rule for Infective Endocarditis in the Emergency Department (CREED) score. To validate the CREED score we …
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M Covino, A De Vita, A d'Aiello, SE Ravenna, A Ruggio… - Journal of the American Heart Association, 2023