作者
Puxiang Lai, Xiao Xu, Honglin Liu, Lihong V Wang
发表日期
2012/3/1
期刊
Journal of Biomedical Optics
卷号
17
期号
3
页码范围
030506-030506
出版商
Society of Photo-Optical Instrumentation Engineers
简介
We report an experimental investigation of time-reversed ultrasonically encoded optical focusing in biological tissue. This technology combines the concepts of optical phase conjugation and ultrasound modulation of diffused coherent light. The ultrasonically encoded (or tagged) diffused light from a tissue sample is collected in reflection mode and interferes with a reference light in a photorefractive crystal (used as a phase conjugation mirror) to form a hologram. Then a time-reversed copy of the tagged light is generated and traces back the original trajectories to the ultrasonic focus inside the tissue sample. With our current setup, we can achieve a maximum penetration depth of 5 mm in a chicken breast sample and image optical contrasts within a tissue sample with a spatial resolution approximately equaling of the ultrasound focal diameter.
学术搜索中的文章
P Lai, X Xu, H Liu, LV Wang - Journal of Biomedical Optics, 2012