作者
Puxiang Lai, Xiao Xu, Honglin Liu, Yuta Suzuki, Lihong V Wang
发表日期
2011/8/11
期刊
Journal of Biomedical Optics
卷号
16
期号
8
页码范围
080505-080505-3
出版商
Society of Photo-Optical Instrumentation Engineers
简介
Time-reversed ultrasonically encoded (TRUE) optical focusing was recently proposed to deliver light dynamically to a tight region inside a scattering medium. In this letter, we report the first development of a reflection-mode TRUE optical focusing system. A high numerical aperture light guide is used to transmit the diffusely reflected light from a turbid medium to a phase-conjugate mirror (PCM), which is sensitive only to the ultrasound-tagged light. From the PCM, a phase conjugated wavefront of the tagged light is generated and conveyed by the same light guide back to the turbid medium, subsequently converging to the ultrasonic focal zone. We present experimental results from this system, which has the ability to focus light in a highly scattering medium with a round-trip optical penetration thickness (extinction coefficient multiplied by round-trip depth) as large as 160.
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