作者
Ting Gong, Jianhua Xuan, Yitan Zhu, Huai Li, Robert Clarke, Eric P Hoffman, Yue Wang
发表日期
2006/7/13
研讨会论文
2006 IEEE/NLM Life Science Systems and Applications Workshop
页码范围
1-2
出版商
IEEE
简介
Gene module discovery can provide comprehensive molecular portrait of biological regulation and functional genomics. We present a new analytic strategy - nonnegative independent component analysis to reveal some gene module composite. The results show that by grouping genes in the latent space, we can find statistically more significant enrichment of gene annotations within clusters. Further, this approach has been applied to a muscular dystrophy data set for gene module discovery
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T Gong, J Xuan, Y Zhu, H Li, R Clarke, EP Hoffman… - 2006 IEEE/NLM Life Science Systems and Applications …, 2006