作者
Vera Gorbunova, Andrei Seluanov, Zhengdong Zhang, Vadim N Gladyshev, Jan Vijg
发表日期
2014/8
来源
Nature Reviews Genetics
卷号
15
期号
8
页码范围
531-540
出版商
Nature Publishing Group UK
简介
Mammals have evolved a remarkable diversity of ageing rates. Within the single order of Rodentia, maximum lifespans range from 4 years in mice to 32 years in naked mole rats. Cancer rates also differ substantially between cancer-prone mice and almost cancer-proof naked mole rats and blind mole rats. Recent progress in rodent comparative biology, together with the emergence of whole-genome sequence information, has opened opportunities for the discovery of genetic factors that control longevity and cancer susceptibility.
学术搜索中的文章
V Gorbunova, A Seluanov, Z Zhang, VN Gladyshev… - Nature Reviews Genetics, 2014