作者
Shivaani Kummar, Robert Kinders, Martin E Gutierrez, Larry Rubinstein, Ralph E Parchment, Lawrence R Phillips, Jiuping Ji, Anne Monks, Jennifer A Low, Alice Chen, Anthony J Murgo, Jerry Collins, Seth M Steinberg, Helen Eliopoulos, Vincent L Giranda, Gary Gordon, Lee Helman, Robert Wiltrout, Joseph E Tomaszewski, James H Doroshow
发表日期
2009/6/6
期刊
Journal of clinical oncology
卷号
27
期号
16
页码范围
2705
出版商
American Society of Clinical Oncology
简介
Purpose
We conducted the first phase 0 clinical trial in oncology of a therapeutic agent under the Exploratory Investigational New Drug Guidance of the US Food and Drug Administration. It was a first-in-human study of the poly (ADP-ribose) polymerase (PARP) inhibitor ABT-888 in patients with advanced malignancies.
引用总数
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S Kummar, R Kinders, ME Gutierrez, L Rubinstein… - Journal of clinical oncology, 2009