作者
Esther Walton, Derrek P Hibar, Theo GM van Erp, Steven G Potkin, Roberto Roiz‐Santiañez, Benedicto Crespo‐Facorro, Paula Suarez‐Pinilla, Neeltje EM Van Haren, Sonja MC de Zwarte, Rene S Kahn, Wiepke Cahn, Nhat Trung Doan, Kjetil N Jørgensen, Tiril P Gurholt, Ingrid Agartz, Ole A Andreassen, Lars T Westlye, Ingrid Melle, Akiah O Berg, Lynn Mørch‐Johnsen, Ann Færden, Lena Flyckt, Helena Fatouros‐Bergman, Karolinska Schizophrenia Project Consortium (KaSP), EG Jönsson, R Hashimoto, H Yamamori, M Fukunaga, A Preda, P De Rossi, Federica Piras, N Banaj, Valentina Ciullo, Gianfranco Spalletta, Raquel E Gur, Ruben C Gur, Daniel H Wolf, Theodore D Satterthwaite, Lauren M Beard, Iris E Sommer, Sanne Koops, Oliver Gruber, Anja Richter, Bernd Krämer, Sinead Kelly, Gary Donohoe, Colm McDonald, Dara M Cannon, Aiden Corvin, Michael Gill, Annabella Di Giorgio, Alessandro Bertolino, Stephen Lawrie, Thomas Nickson, Heather C Whalley, Emma Neilson, Vince D Calhoun, Paul M Thompson, Jessica A Turner, Stefan Ehrlich, L Farde, G Engberg, S Erhardt, H Fatouros‐Bergman, S Cervenka, L Schwieler, F Piehl, P Ikonen, K Collste, F Orhan, A Malmqvist, M Hedberg
发表日期
2017/5
期刊
Acta Psychiatrica Scandinavica
卷号
135
期号
5
页码范围
439-447
简介
Objective
Based on the role of the superior temporal gyrus (STG) in auditory processing, language comprehension and self‐monitoring, this study aimed to investigate the relationship between STG cortical thickness and positive symptom severity in schizophrenia.
Method
This prospective meta‐analysis includes data from 1987 individuals with schizophrenia collected at seventeen centres around the world that contribute to the ENIGMA Schizophrenia Working Group. STG thickness measures were extracted from T1‐weighted brain scans using FreeSurfer. The study performed a meta‐analysis of effect sizes across sites generated by a model predicting left or right STG thickness with a positive symptom severity score (harmonized SAPS or PANSS‐positive scores), while controlling for age, sex and site. Secondary models investigated relationships between antipsychotic medication, duration of illness, overall …
引用总数
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