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The commercialization of Cloud-RAN, and Open-RAN in particular, is a key factor to enable 5G cell densification by providing lower cost and more agile deployment of small cells. In addition, the adoption of multi-access edge computing (MEC) is important to support the ultra-low latency and high reliability required by mission-critical applications, which constitute a milestone of the 5G and beyond vision of a fully connected society. However, connecting antenna site, C-RAN processing, and MEC at low cost is challenging, as it requires high-capacity, low-latency connectivity delivered through a highly inter-connected topology. While passive optical networks (PONs) are being considered as a solution for providing low-cost connectivity to C-RAN, they only allow data transmission from the endpoints (e.g., hosting the radio unit, RU, at the antenna site) toward a central node (e.g., the central office, hosting computing …