作者
Pea Carninci, T Kasukawa, S Katayama, J Gough, MC Frith, Norihiro Maeda, Rieko Oyama, T Ravasi, B Lenhard, C Wells, Rimantas Kodzius, Kazuro Shimokawa, Vladimir B Bajic, SE Brenner, Serge Batalov, ARR Forrest, Mihaela Zavolan, MJ Davis, Laurens G Wilming, V Aidinis, JE Allen, A Ambesi-Impiombato, R Apweiler, Rajith N Aturaliya, TL Bailey, M Bansal, L Baxter, Kirk W Beisel, T Bersano, H Bono, Alistair M Chalk, KP Chiu, V Choudhary, A Christoffels, DR Clutterbuck, ML Crowe, E Dalla, BP Dalrymple, B De Bono, G Della Gatta, Diego di Bernardo, T Down, P Engstrom, M Fagiolini, G Faulkner, CF Fletcher, T Fukushima, M Furuno, S Futaki, M Gariboldi, P Georgii-Hemming, TR Gingeras, Takashi Gojobori, RE Green, S Gustincich, M Harbers, Yutaka Hayashi, TK Hensch, N Hirokawa, D Hill, L Huminiecki, M Iacono, Kazuho Ikeo, A Iwama, T Ishikawa, M Jakt, A Kanapin, Masaru Katoh, Y Kawasawa, Janet Kelso, H Kitamura, Hiroaki Kitano, G Kollias, SPT Krishnan, A Kruger, SK Kummerfeld, IV Kurochkin, LF Lareau, D Lazarevic, L Lipovich, J Liu, S Liuni, S McWilliam, M Madan Babu, M Madera, Luigi Marchionni, Hideo Matsuda, S Matsuzawa, H Miki, F Mignone, S Miyake, K Morris, Salim Mottagui-Tabar, N Mulder, N Nakano, H Nakauchi, P Ng, R Nilsson, S Nishiguchi, S Nishikawa, F Nori, O Ohara, Y Okazaki, V Orlando, KC Pang, WJ Pavan, G Pavesi, G Pesole, Nikolai Petrovsky, S Piazza, J Reed, JF Reid, Brian Z Ring, M Ringwald, B Rost, Y Ruan, Steven L Salzberg, A Sandelin, C Schneider, C Schonbach, K Sekiguchi, Colin AM Semple, S Seno, L Sessa, Y Sheng, Y Shibata, H Shimada, K Shimada, D Silva, B Sinclair, S Sperling, E Stupka, Koji Sugiura, R Sultana, Yoichi Takenaka, K Taki, K Tammoja, SL Tan, S Tang, MS Taylor, J Tegner, SA Teichmann, HR Ueda, E Van Nimwegen, R Verardo, CL Wei, K Yagi, H Yamanishi, E Zabarovsky, S Zhu
发表日期
2005/9/2
期刊
science
卷号
309
期号
5740
页码范围
1559-1563
出版商
American Association for the Advancement of Science
简介
This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5′ and 3′ boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.
引用总数
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