作者
Darrell Triulzi, Jerome Gottschall, Edward Murphy, Yanyun Wu, Paul Ness, Daryl Kor, Nareg Roubinian, Debra Fleischmann, Dhuly Chowdhury, Donald Brambilla, NHLBI Recipient Epidemiology and Donor Evaluation Study‐III (REDS‐III)
发表日期
2015/6
期刊
Transfusion
卷号
55
期号
6
页码范围
1313-1319
简介
Background
Detailed information regarding plasma use in the United States is needed to identify opportunities for practice improvement and design of clinical trials of plasma therapy.
Study Design and Methods
Ten US hospitals collected detailed medical information from the electronic health records for 1 year (2010‐2011) for all adult patients transfused with plasma.
Results
A total of 72,167 units of plasma were transfused in 19,596 doses to 9269 patients. The median dose of plasma was 2 units (interquartile range, 2‐4; range 1‐72); 15% of doses were 1 unit, and 45% were 2 units. When adjusted by patient body weight (kg), the median dose was 7.3 mL/kg (interquartile range, 5.5‐12.0). The median pretransfusion international normalized ratio (INR) was 1.9 (25%‐75% interquartile range, 1.6‐2.6). A total of 22.5% of plasma transfusions were given to patients with an INR of less than 1.6 and 48.5% for an …
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D Triulzi, J Gottschall, E Murphy, Y Wu, P Ness, D Kor… - Transfusion, 2015