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E‐learning has been used recently in dental curricula to support traditional learning methods. However, the published literature concerning e‐learning in oral radiology has shown mixed conclusions. The aim of this systematic review was to provide a synthesis of the effectiveness of e‐learning in oral radiology education when compared with traditional classroom learning methods. A search of the literature was conducted on the LILACS, PubMed, Science Direct, Scopus, and Web of Science databases. Trials registries were also consulted for ongoing trials, and a partial grey literature search was conducted. Controlled trials about oral radiology education that compared any e‐learning method with a control group using any traditional classroom instruction method were included. E‐learning effectiveness was measured using three outcomes from Kirkpatrick's model of evaluation: attitudes about e‐learning …