作者
Tellen D Bennett, Richard A Moffitt, Janos G Hajagos, Benjamin Amor, Adit Anand, Mark M Bissell, Katie Rebecca Bradwell, Carolyn Bremer, James Brian Byrd, Alina Denham, Peter E DeWitt, Davera Gabriel, Brian T Garibaldi, Andrew T Girvin, Justin Guinney, Elaine L Hill, Stephanie S Hong, Hunter Jimenez, Ramakanth Kavuluru, Kristin Kostka, Harold P Lehmann, Eli Levitt, Sandeep K Mallipattu, Amin Manna, Julie A McMurry, Michele Morris, John Muschelli, Andrew J Neumann, Matvey B Palchuk, Emily R Pfaff, Zhenglong Qian, Nabeel Qureshi, Seth Russell, Heidi Spratt, Anita Walden, Andrew E Williams, Jacob T Wooldridge, Yun Jae Yoo, Xiaohan Tanner Zhang, Richard L Zhu, Christopher P Austin, Joel H Saltz, Ken R Gersing, Melissa A Haendel, Christopher G Chute, Joel Gagnier, Siqing Hu, Kanchan Lota, Sarah Maidlow, David A Hanauer, Kevin Weatherwax, Nikhila Gandrakota, Rishikesan Kamaleswaran, Greg Martin, Jingjing Qian, Jason E Farley, Patricia A Francis, Dazhi Jiao, Hadi Kharrazi, Justin T Reese, Mariam Deacy, Usman Sheikh, Jake Chen, Michael Patton, Thomas Ramsey, Jasvinder Singh, James J Cimino, Jing Su, William G Adams, Tim Duong, John B Buse, Jessica Yasmine Islam, Jihad S Obeid, Stephane Meystre, Steve Patterson, Misha Zemmel, Ron Grider, Ashley Martinez, Carlos Santos, Julian Solway, Ryan Chiu, Gerald B Brown, Jiafeng Cui, Sharon Liang, Kamil Khanipov, Jeremy Richard Harper, Peter J Embi, David A Eichmann, Boyd M Knosp, William Hillegass, Chunlei Wu, James Aaron, Darren Henderson, Muhammad Gul, Tamela Harper, Daniel Harris, Jeff Talbert, Neil Bahroos, Steven Dubinett, Jomol Mathew, Gabriel McMahan, Hongfang Liu, Claudia Lucchinetti, David L Schwartz, Ralph Sacco, Peyman Taghioff, Diane Harper, Denise Angst, Andrew Marek, Carlos E Figueroa Castro, Bruce Blazar, Steven G Johnson, Melissa Basford, Laura Jones, Gordon Bernard, Rosalind Wright, Joseph Finkelstein, Thomas R Campion, Christopher E Mason, Xiaobo Fuld, Alfred Anzalone, James C McClay, Shyam Visweswaran, Connor Cook, Alexandra Dest, David Ellison, Rose Relevo, Andrea M Volz, Chengda Zhang, Martha Tenzer, David S Bowers, Francis Farrell, Qiuyuan Qin, Martin Zand, Jeanne Holden-Wiltse, Ramkiran Gouripeddi, Julio Facelli, Robert Clark, Benjamin Becerra, Yao Yan, Jimmy Phuong, Yooree Chae, Rena C Patel, Christine Suver, Elizabeth Zampino, Ahmed S Said, Philip RO Payne, Randeep Jawa, Peter L Elkin, Farrukh M Koraishy
发表日期
2021/7/1
期刊
JAMA network open
卷号
4
期号
7
页码范围
e2116901-e2116901
出版商
American Medical Association
简介
Importance
The National COVID Cohort Collaborative (N3C) is a centralized, harmonized, high-granularity electronic health record repository that is the largest, most representative COVID-19 cohort to date. This multicenter data set can support robust evidence-based development of predictive and diagnostic tools and inform clinical care and policy.
Objectives
To evaluate COVID-19 severity and risk factors over time and assess the use of machine learning to predict clinical severity.
Design, Setting, and Participants
In a retrospective cohort study of 1 926 526 US adults with SARS-CoV-2 infection (polymerase chain reaction >99% or antigen <1%) and adult patients without SARS-CoV-2 infection who served as controls from 34 medical centers nationwide between January 1, 2020, and December 7, 2020, patients were stratified using a World Health Organization COVID-19 severity scale and demographic …
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TD Bennett, RA Moffitt, JG Hajagos, B Amor, A Anand… - JAMA network open, 2021