作者
Edoardo Caronna, Alejandro Ballvé, Arnau Llauradó, Victor José Gallardo, Diana María Ariton, Sofia Lallana, Samuel Lopez Maza, Marta Olive Gadea, Laura Quibus, Juan Luis Restrepo, Marc Rodrigo-Gisbert, Andreu Vilaseca, Manuel Hernandez Gonzalez, Monica Martinez Gallo, Alicia Alpuente, Marta Torres-Ferrus, Ricard Pujol Borrell, José Alvarez-Sabin, Patricia Pozo-Rosich
发表日期
2020/11
期刊
Cephalalgia
卷号
40
期号
13
页码范围
1410-1421
出版商
SAGE Publications
简介
Objective
To define headache characteristics and evolution in relation to COVID-19 and its inflammatory response.
Methods
This is a prospective study, comparing clinical data and inflammatory biomarkers of COVID-19 patients with and without headache, recruited at the Emergency Room. We compared baseline with 6-week follow-up to evaluate disease evolution.
Results
Of 130 patients, 74.6% (97/130) had headache. In all, 24.7% (24/97) of patients had severe pain with migraine-like features. Patients with headache had more anosmia/ageusia (54.6% vs. 18.2%; p < 0.0001). Clinical duration of COVID-19 was shorter in the headache group (23.9 ± 11.6 vs. 31.2 ± 12.0 days; p = 0.028). In the headache group, IL-6 levels were lower at the ER (22.9 (57.5) vs. 57.0 (78.6) pg/mL; p = 0.036) and more stable during hospitalisation. After 6 weeks, of 74 followed-up patients with headache, 37.8% (28/74) had …
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E Caronna, A Ballvé, A Llauradó, VJ Gallardo… - Cephalalgia, 2020