作者
Mercedes R Carnethon, Peter John D De Chavez, Mary L Biggs, Cora E Lewis, James S Pankow, Alain G Bertoni, Sherita H Golden, Kiang Liu, Kenneth J Mukamal, Brenda Campbell-Jenkins, Alan R Dyer
发表日期
2012/8/8
期刊
Jama
卷号
308
期号
6
页码范围
581-590
出版商
American Medical Association
简介
Context
Type 2 diabetes in normal-weight adults (body mass index [BMI] <25) is a representation of the metabolically obese normal-weight phenotype with unknown mortality consequences.
Objective
To test the association of weight status with mortality in adults with new-onset diabetes in order to minimize the influence of diabetes duration and voluntary weight loss on mortality.
Design, Setting, and Participants
Pooled analysis of 5 longitudinal cohort studies: Atherosclerosis Risk in Communities study, 1990-2006; Cardiovascular Health Study, 1992-2008; Coronary Artery Risk Development in Young Adults, 1987-2011; Framingham Offspring Study, 1979-2007; and Multi-Ethnic Study of Atherosclerosis, 2002-2011. A total of 2625 participants with incident diabetes contributed 27 125 person-years of follow-up. Included were men and women (age >40 years) who developed incident diabetes based on fasting glucose …
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MR Carnethon, PJD De Chavez, ML Biggs, CE Lewis… - Jama, 2012