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The novel coronavirus had entirely changed the health sector. A parallel wing of telemedicine had blossomed rapidly in this critical phase to treat noninvasive and nonemergency patients. In the field of COVID-19 telehealth, Internet technology and nature-motivated innovations help to transmit the private and confidential information present in multiple cardiological reports. These reports can be sent to different cardiologists for better treatments, opinions, and research purposes. These cardiac reports must be protected against intruders in order to maintain patients’ confidentiality. The cardiac reports should be converted into nonreadable text for the intruders, which is the main objective of this chapter. Music-key has been derived through a nature-motivated harmony search metaheuristic algorithm followed by classical AES cryptography. Cardiovascular diseases (CVDs) are one of the cardiac diseases connected to …