作者
Wei-Ning Lee, Jean Provost, Kana Fujikura, Jie Wang, Elisa E Konofagou
发表日期
2011/2/1
期刊
Physics in Medicine & Biology
卷号
56
期号
4
页码范围
1155
出版商
IOP Publishing
简介
The capability of currently available echocardiography-based strain estimation techniques to fully map myocardial abnormality at early stages of myocardial ischemia is yet to be investigated. In this study, myocardial elastography (ME), a radio-frequency (RF)-based strain imaging technique that maps the full 2D transmural angle-independent strain tensor in standard echocardiographic views at both high spatial and temporal resolution is presented. The objectives were to (1) evaluate the performance of ME on mapping the onset, extent and progression of myocardial ischemia at graded coronary constriction levels (from partial to complete coronary flow reduction), and (2) validate the accuracy of the strain estimates against sonomicrometry (SM) measurements. A non-survival canine ischemic model (n= 5) was performed by gradually constricting the left anterior descending (LAD) coronary blood flow from 0 …
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WN Lee, J Provost, K Fujikura, J Wang, EE Konofagou - Physics in Medicine & Biology, 2011