作者
Zsanett Bahor, Jing Liao, Malcolm R Macleod, Alexandra Bannach-Brown, Sarah K McCann, Kimberley E Wever, James Thomas, Thomas Ottavi, David W Howells, Andrew Rice, Sophia Ananiadou, Emily Sena
发表日期
2017/10/15
来源
Clinical Science
卷号
131
期号
20
页码范围
2525-2532
出版商
Portland Press Limited
简介
Background: Findings from in vivo research may be less reliable where studies do not report measures to reduce risks of bias. The experimental stroke community has been at the forefront of implementing changes to improve reporting, but it is not known whether these efforts are associated with continuous improvements. Our aims here were firstly to validate an automated tool to assess risks of bias in published works, and secondly to assess the reporting of measures taken to reduce the risk of bias within recent literature for two experimental models of stroke.
Methods: We developed and used text analytic approaches to automatically ascertain reporting of measures to reduce risk of bias from full-text articles describing animal experiments inducing middle cerebral artery occlusion (MCAO) or modelling lacunar stroke.
Results: Compared with previous assessments, there were improvements in the reporting …
学术搜索中的文章
Z Bahor, J Liao, MR Macleod, A Bannach-Brown… - Clinical Science, 2017