作者
Eisuke Nakao, Ken Namikawa, Toshiaki Hirasawa, Kaoru Nakano, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Souya Nunobe, Junko Fujisaki
发表日期
2022/3
期刊
JGH Open
卷号
6
期号
3
页码范围
189-195
出版商
Wiley Publishing Asia Pty Ltd
简介
Background and Aim
The risk factors for lymph node metastasis (LNM) of duodenal neuroendocrine tumors (DNETs) are not well identified, and a definitive standard of treatment for DNETs has not been established. In this study, we aimed to identify the risk factors for LNM and establish the indication of local resection for DNETs.
Methods
We retrospectively reviewed 55 patients with 60 non‐ampullary and nonfunctional DNETs. We evaluated the risk factors for LNM and compared the outcomes between endoscopic resection (ER) for DNETs <5 mm and laparoscopy and endoscopy cooperative surgery (LECS) for DNETs ≥5 mm.
Results
LNM was present in four (8.7%) patients. Univariate analysis revealed that tumor size ≥10 mm, positive lymphovascular invasion (LVI), and 0‐Is morphology were significantly associated with LNM (P = 0.008, P = 0.037, and P = 0.045, respectively). ER and LECS were …
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E Nakao, K Namikawa, T Hirasawa, K Nakano, Y Tokai… - JGH Open, 2022