作者
Shadi Yaghi, Liqi Shu, Ekaterina Bakradze, Setareh Salehi Omran, James A Giles, Jordan Y Amar, Nils Henninger, Marwa Elnazeir, Ava L Liberman, Khadean Moncrieffe, Jenny Lu, Richa Sharma, Yee Cheng, Adeel S Zubair, Alexis N Simpkins, Grace T Li, Justin Chi Kung, Dezaray Perez, Mirjam Heldner, Adrian Scutelnic, David Seiffge, Bernhard Siepen, Aaron Rothstein, Ossama Khazaal, David Do, Sami Al Kasab, Line Abdul Rahman, Eva A Mistry, Deborah Kerrigan, Hayden Lafever, Thanh N Nguyen, Piers Klein, Hugo Aparicio, Jennifer Frontera, Lindsey Kuohn, Shashank Agarwal, Christoph Stretz, Narendra Kala, Sleiman El Jamal, Alison Chang, Shawna Cutting, Han Xiao, Adam De Havenon, Varsha Muddasani, Teddy Wu, Duncan Wilson, Amre Nouh, Syed Daniyal Asad, Abid Qureshi, Justin Moore, Pooja Khatri, Yasmin Aziz, Bryce Casteigne, Muhib Khan, Yao Cheng, Brian Mac Grory, Martin Weiss, Dylan Ryan, Maria Cristina Vedovati, Maurizio Paciaroni, James E Siegler, Scott Kamen, Siyuan Yu, Christopher R Leon Guerrero, Eugenie Atallah, Gian Marco De Marchis, Alex Brehm, Tolga Dittrich, Marios Psychogios, Ronald Alvarado-Dyer, Tareq Kass-Hout, Shyam Prabhakaran, Tristan Honda, David S Liebeskind, Karen Furie
发表日期
2022/3
期刊
Stroke
卷号
53
期号
3
页码范围
728-738
出版商
Lippincott Williams & Wilkins
简介
Background
A small randomized controlled trial suggested that dabigatran may be as effective as warfarin in the treatment of cerebral venous thrombosis (CVT). We aimed to compare direct oral anticoagulants (DOACs) to warfarin in a real-world CVT cohort.
Methods
This multicenter international retrospective study (United States, Europe, New Zealand) included consecutive patients with CVT treated with oral anticoagulation from January 2015 to December 2020. We abstracted demographics and CVT risk factors, hypercoagulable labs, baseline imaging data, and clinical and radiological outcomes from medical records. We used adjusted inverse probability of treatment weighted Cox-regression models to compare recurrent cerebral or systemic venous thrombosis, death, and major hemorrhage in patients treated with warfarin versus DOACs. We performed adjusted inverse probability of treatment weighted …
学术搜索中的文章
S Yaghi, L Shu, E Bakradze, S Salehi Omran, JA Giles… - Stroke, 2022