作者
Shuji Akimoto, Takashi Onoe, Hiroshi Morimoto, Shinji Yamaguchi, Yoshiyuki Shibata, Sho Tazuma, Haruki Sada, Norimitsu Shimada, Hirofumi Tazawa, Takahisa Suzuki, Takeshi Sudo, Yosuke Shimizu, Hirotaka Tashiro
发表日期
2023/5/1
期刊
Transplantation Proceedings
卷号
55
期号
4
页码范围
815-819
出版商
Elsevier
简介
Background
This study confirmed the kinetics of antibodies acquired by SARS-CoV-2 vaccination in solid-organ transplant recipients and examined their association with the development of COVID-19 and immunosuppressive status in organ transplant recipients.
Methods
We measured COVID-19 neutralizing antibody titer in 21 organ transplant recipients vaccinated with the COVID-19 vaccine and 14 nontransplant recipients (control group) 3 times before and at 1 and 6 months after the third dose of vaccine. By confirming the kinetics of the acquired antibodies, we examined the relevance of the background characteristics of organ transplant recipients, such as the development of infectious diseases and immunosuppressive status.
Results
The proportion of patients with neutralizing antibodies was significantly higher in the nontransplant group than in the transplant group. Neutralizing antibody titers were significantly …
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S Akimoto, T Onoe, H Morimoto, S Yamaguchi… - Transplantation Proceedings, 2023