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Initial spurt in agricultural growth rate as a result of the “First Green Revolution” has experienced distinct slowdown in recent years. There is urgent need to enhance productivity through technological as Nanotechnology, intervention. It is one of the emerging technologies with enormous agricultural application, which can be effectively applied in the development and design of methods and instrumentation for enhancing quantity and quality of food products and managing environment in better way. The paper discusses feasibility of achieving Second Green Revolution in India through nanotechnological application in agriculture in India.