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Rapid advances in technology for highly automated vehicles (HAVs) have raised concerns about coexistence of HAVs and human road users. Although there is a long tradition of research into human road user interactions, there is a lack of shared models and terminology to support cross-disciplinary research and development towards safe and acceptable interaction-capable HAVs. Here, we review the main themes and findings in previous theoretical and empirical interaction research, and find large variability in perspectives and terminologies. We unify these perspectives in a structured, cross-theoretical conceptual framework, describing what road traffic interactions are, how they arise, and how they get resolved. Two key contributions are: (1) a stringent definition of “interaction”, as “a situation where the behaviour of at least two road users can be interpreted as being influenced by the possibility that they are …