作者
Geoffrey M Attardo, Adly MM Abd-Alla, Alvaro Acosta-Serrano, James E Allen, Rosemary Bateta, Joshua B Benoit, Kostas Bourtzis, Jelle Caers, Guy Caljon, Mikkel B Christensen, David W Farrow, Markus Friedrich, Aurélie Hua-Van, Emily C Jennings, Denis M Larkin, Daniel Lawson, Michael J Lehane, Vasileios P Lenis, Ernesto Lowy-Gallego, Rosaline W Macharia, Anna R Malacrida, Heather G Marco, Daniel Masiga, Gareth L Maslen, Irina Matetovici, Richard P Meisel, Irene Meki, Veronika Michalkova, Wolfgang J Miller, Patrick Minx, Paul O Mireji, Lino Ometto, Andrew G Parker, Rita Rio, Clair Rose, Andrew J Rosendale, Omar Rota-Stabelli, Grazia Savini, Liliane Schoofs, Francesca Scolari, Martin T Swain, Peter Takáč, Chad Tomlinson, George Tsiamis, Jan Van Den Abbeele, Aurelien Vigneron, Jingwen Wang, Wesley C Warren, Robert M Waterhouse, Matthew T Weirauch, Brian L Weiss, Richard K Wilson, Xin Zhao, Serap Aksoy
发表日期
2019/12
期刊
Genome biology
卷号
20
页码范围
1-31
出版商
BioMed Central
简介
Background
Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood-specific diet by both sexes, and obligate bacterial symbiosis. This work describes the comparative analysis of six Glossina genomes representing three sub-genera: Morsitans (G. morsitans morsitans, G. pallidipes, G. austeni), Palpalis (G. palpalis, G. fuscipes), and Fusca (G. brevipalpis) which represent different habitats, host preferences, and vectorial capacity.
Results
Genomic analyses validate established evolutionary relationships and sub-genera. Syntenic analysis of Glossina relative to Drosophila melanogaster shows reduced structural conservation across the sex …
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