作者
Daniel Modin, Sofie Reumert Biering-Sørensen, Rasmus Møgelvang, Jan Skov Jensen, Tor Biering-Sørensen
发表日期
2018/10
期刊
Circulation: Cardiovascular Imaging
卷号
11
期号
10
页码范围
e007528
出版商
Lippincott Williams & Wilkins
简介
Background
Cardiovascular death (CVD) is a leading cause of death and constitutes a major burden on society. Left ventricular mechanical dyssynchrony (LVMD), evaluated as SD of time to peak regional longitudinal strain, is a capable predictor of many cardiovascular outcomes related to CVD, including ventricular arrhythmias, but the prognostic utility of LVMD in the general population is unknown. Hence, this study sought to determine the prognostic value of LVMD in the general population in predicting CVD.
Methods and Results
A total of 1138 participants underwent a general health examination and an echocardiographic examination including speckle tracking analysis with subsequent calculation of LVMD from time-to-peak regional strain. Primary end point was CVD, and secondary end point was noncardiovascular death. Follow-up was 100%. During a median follow-up of 11.1 years (interquartile range …
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D Modin, SR Biering-Sørensen, R Møgelvang… - Circulation: Cardiovascular Imaging, 2018