作者
Ingrid Josefine Lundorff, Morten Sengeløv, Peter Godsk Jørgensen, Sune Pedersen, Daniel Modin, Niels Eske Bruun, Thomas Fritz-Hansen, Jan Skov Jensen, Tor Biering-Sørensen
发表日期
2018/11
期刊
Circulation: Cardiovascular Imaging
卷号
11
期号
11
页码范围
e008031
出版商
Lippincott Williams & Wilkins
简介
Background
Previous studies found that global longitudinal strain is a superior predictor of mortality in male patients with heart failure with reduced ejection fraction (EF). This does not apply to women. Our aim was to investigate sex-specific differences in cardiac function and identify echocardiographic predictors of mortality in women with heart failure with reduced EF.
Methods and Results
Echocardiographic examinations were retrieved from 968 patients with heart failure with reduced EF (26.7% women). Images were analyzed offline, and the end point was all-cause mortality. During follow-up (median: 41 months) 163 patients (16.8 %) died. Women had significantly higher left ventricular (LV) EF (27.1% versus 25.4%, P=0.004), global longitudinal strain (−9.9% versus −8.9%, P<0.001), and global circumferential strain (−10.9% versus −9.7%, P<0.001). Moreover, women displayed higher E/e′ (14.4 versus 13.0 …
学术搜索中的文章
Echocardiographic predictors of mortality in women with heart failure with reduced ejection fraction
IJ Lundorff, M Sengeløv, PG Jørgensen, S Pedersen… - Circulation: Cardiovascular Imaging, 2018