作者
Ju-Young Shin, Sohyun Jeong, Ha-Lim Jeon, Seongjun Byun, Kyu Hyung Park, Han Eol Jeong, Sang Jun Park
发表日期
2018/12/1
期刊
Journal of Antimicrobial Chemotherapy
卷号
73
期号
12
页码范围
3442-3453
出版商
Oxford University Press
简介
Objectives
To determine whether or not fluoroquinolone use increases the incidence of retinal detachment.
Design
Self-controlled case series analysis.
Participants
Participants were identified using the South Korean National Health Insurance Database between 1 January 2004 and 31 December 2015. A total of 15 134 patients who experienced rhegmatogenous retinal detachment (RRD) with at least one prescription of a fluoroquinolone were included.
Methods
Incidence rate ratios (IRRs) and their 95% CIs were calculated using conditional Poisson regression. The main outcome measure was a recorded diagnosis of RRD (ICD-10: H33.0) with a claim for the surgical code for RRD.
Results
We found an increased risk of retinal detachment in the first 1–30 days following the initiation of fluoroquinolone therapy …
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