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Gastric Cancer (GC) has been identified as the world’s fifth most general tumor. So, it is important to diagnose the GC at initial stages itself to save the lives. Histopathological analysis remains the gold standard for accurate diagnosis of the disease. Though Computer-Aided Diagnostic approaches are prevalently applied in recent years for the diagnosis of diseases, it is challenging to apply in this case, due to the lack of accessible gastric histopathological image databases. With a rapid progression in the Computer Vision (CV) technologies, particularly, the emergence of medicinal image classifiers, it has become feasible to examine all the types of electron micrographs in a rapid and an effective manner. Therefore, the current research article presents an Anas Platyrhynchos Optimizer with Deep Learning-based Gastric Cancer Classification (APODL-GCC) method for the classification of GC using the endoscopic images. The aim of the proposed APODL-GCC method is to identify the presence of GC with the help of CV and Deep Learning concepts. Primarily, the APODL-GCC technique employs a contrast enhancement technique. Next, the feature extraction process is performed using a neural architectural search network model to generate a collection of feature vectors. For