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Coordinated multi-point transmission/reception (CoMP) has been considered in 3GPP LTE-Advanced to improve system performance, especially cell edge throughput. The conventional uplink power control (PC) scheme cannot work well since a UE can be served by multiple cells. This paper analyzes uplink PC issues in detail, and proposes an effective scheme aiming to obtain the reception diversity gain from CoMP. System-level simulation results have shown that CoMP systems with both the conventional scheme and the proposed scheme can achieve a better cell edge performance, compared with non-CoMP systems. Furthermore, the proposed scheme considerably outperforms the conventional scheme, it can bring an additional cell average throughput gain up to 15.78% and an additional cell edge throughput gain up to 69.22% over the conventional scheme, thus is recommended to be adopted in CoMP …