作者
Mustafa Alshawaqfeh, Salahelden Rababah, Abdullah Hayajneh, Ammar Gharaibeh, Erchin Serpedin
发表日期
2022/12/28
期刊
BMC Medical Research Methodology
卷号
22
期号
1
页码范围
336
出版商
BioMed Central
简介
Background
Many metagenomic studies have linked the imbalance in microbial abundance profiles to a wide range of diseases. These studies suggest utilizing the microbial abundance profiles as potential markers for metagenomic-associated conditions. Due to the inevitable importance of biomarkers in understanding the disease progression and the development of possible therapies, various computational tools have been proposed for metagenomic biomarker detection. However, most existing tools require prior scripting knowledge and lack user friendly interfaces, causing considerable time and effort to install, configure, and run these tools. Besides, there is no available all-in-one solution for running and comparing various metagenomic biomarker detection simultaneously. In addition, most of these tools just present the suggested biomarkers without any statistical evaluation for their quality.
Results
To …
引用总数
学术搜索中的文章