作者
Kalpana Ramanna Mali, Madhavi Eerike, Gerard Marshall Raj, Debasis Bisoi, Rekha Priyadarshini, Gandham Ravi, Leo Francis Chaliserry, Siddharam S Janti
发表日期
2023/8
来源
Irish Journal of Medical Science (1971-)
卷号
192
期号
4
页码范围
1665-1678
出版商
Springer International Publishing
简介
Background
Molnupiravir is an oral antiviral drug that received Emergency Use Authorization in three countries for the treatment of mild COVID-19. The aim of this systematic review was to find out the safety and efficacy of Molnupiravir in SARS-COV-2 infections.
Methods
The electronic databases such as PubMed, MedRxiv, BioRxiv, FDA, ClinicalTrials.Gov, ctri.nic.in and Google Scholar were searched for articles from January 2021 to March 2022 using the keywords such as “Molnupiravir”, “COVID-19”, “Oral antiviral pill”, “MK-4482”, “EIDD-280”, “Efficacy” and “Safety”. Details of published, unpublished with interim reports and ongoing studies of Molnupiravir in COVID-19 were retrieved, and a systematic review was performed.
Results
A total of 6 articles and 18 ongoing trials data were collected. Out of these, data from 4 published and 2 unpublished with interim reports were extracted. After review of these studies, it …
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KR Mali, M Eerike, GM Raj, D Bisoi, R Priyadarshini… - Irish Journal of Medical Science (1971-), 2023