作者
Melanie E Inkster, Tom P Fahey, Peter T Donnan, Graham P Leese, Gary J Mires, Deirdre J Murphy
发表日期
2006/12
来源
BMC pregnancy and childbirth
卷号
6
页码范围
1-13
出版商
BioMed Central
简介
Background
Glycaemic control in women with diabetes is critical to satisfactory pregnancy outcome. A systematic review of two randomised trials concluded that there was no clear evidence of benefit from very tight versus tight glycaemic control for pregnant women with diabetes.
Methods
A systematic review of observational studies addressing miscarriage, congenital malformations and perinatal mortality among pregnant women with type 1 and type 2 diabetes was carried out. Literature searches were performed in MEDLINE, EMBASE, CINAHL and Cochrane Library. Observational studies with data on glycated haemoglobin (HbA1c) levels categorised into poor and optimal control (as defined by the study investigators) were selected. Relative risks and odds ratios were calculated for HbA1c and pregnancy outcomes. Adjusted relative risk estimates per …
引用总数
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学术搜索中的文章
ME Inkster, TP Fahey, PT Donnan, GP Leese, GJ Mires… - BMC pregnancy and childbirth, 2006