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Transportation agencies have started including phased deployment of connected and automated vehicle (CAV) technologies in their transportation plans and programs. While theoretical analyses have indicated significant benefits of CAVs for improving system performance, deploying these technologies at existing or adapted highway facilities concerns more than technological issues. This study introduces the concepts and operational strategies of using managed lanes, High-Occupancy Vehicle (HOV) lanes in particular, for mixed-autonomy traffic management. The study enhances existing and develops new algorithms for three selected freeway CAV applications as a CAV technology integration, including speed harmonization, cooperative adaptive cruise control (CACC), and cooperative merge. Instead of evaluation on a synthetic segment, this study reports a large-scale simulation-based real-world case study …