作者
Pilwon Kim, Chang Hyeong Lee
发表日期
2012/6/21
期刊
The Journal of Chemical Physics
卷号
136
期号
23
出版商
AIP Publishing
简介
In this paper we present a probability generating function (PGF) approach for analyzing stochastic reaction networks. The master equation of the network can be converted to a partial differential equation for PGF. Using power series expansion of PGF and Padé approximation, we develop numerical schemes for finding probability distributions as well as first and second moments. We show numerical accuracy of the method by simulating chemical reaction examples such as a binding-unbinding reaction, an enzyme-substrate model, Goldbeter-Koshland ultrasensitive switch model, and G 2/M transition model.
引用总数
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