作者
Pranita D Tamma, Edina Avdic, John F Keenan, Yuan Zhao, Gobind Anand, James Cooper, Rebecca Dezube, Steven Hsu, Sara E Cosgrove
发表日期
2017/3/1
期刊
Clinical Infectious Diseases
卷号
64
期号
5
页码范围
537-543
出版商
Oxford University Press
简介
Background
The optimal approach to conducting antibiotic stewardship interventions has not been defined. We compared days of antibiotic therapy (DOT) using preprescription authorization (PPA) vs postprescription review with feedback (PPRF) strategies.
Methods
A quasi-experimental, crossover trial comparing PPA and PPRF for adult inpatients prescribed any antibiotic was conducted. For the first 4 months, 2 medicine teams were assigned to the PPA arm and the other 2 teams to the PPRF arm. The teams were then assigned to the alternate arm for an additional 4 months. Appropriateness of antibiotic use was adjudicated by at least 2 infectious diseases–trained clinicians and according to institutional guidelines.
Results. There were 2686 and 2693 patients admitted to the PPA and PPRF groups, with
29% and 27% of patients prescribed antibiotics …
学术搜索中的文章
PD Tamma, E Avdic, JF Keenan, Y Zhao, G Anand… - Clinical Infectious Diseases, 2017