作者
Sanna-Kaisa Herukka, Jaana Rummukainen, Jouni Ihalainen, Mikael von und zu Fraunberg, Anne M Koivisto, Ossi Nerg, Lakshman K Puli, Toni T Seppälä, Henrik Zetterberg, Okko T Pyykkö, Seppo Helisalmi, Heikki Tanila, Irina Alafuzoff, Mikko Hiltunen, Jaakko Rinne, Hilkka Soininen, Juha E Jääskeläinen, Ville Leinonen
发表日期
2015/1/1
期刊
Journal of Alzheimer's Disease
卷号
46
期号
1
页码范围
261-269
出版商
IOS Press
简介
Objective: To assess the relationship between AD-related pathological changes in human brain tissue, ventricular and lumbar CSF, and brain interstitial fluid (ISF).
Methods: Altogether 11 patients with suspected idiopathic normal pressure hydrocephalus underwent frontal cortical brain biopsy, 24-h intraventricular pressure monitoring, and a microdialysis procedure. AD-related biomarkers were analyzed from brain tissue, CSF, and ISF.
引用总数
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