作者
Gül Eryılmaz, Gökben Hızlı Sayar, Eylem Ozten, Işıl Gögcegöz Gül, Oğuz Karamustafalıoğlu
发表日期
2013/12
期刊
Annals of General Psychiatry
卷号
12
页码范围
1-4
出版商
BioMed Central
简介
Objective
Patients with schizophrenia often experience comorbid obsessive-compulsive symptoms. Within these patients, a significant subgroup developed secondary obsessive-compulsive symptoms during treatment with clozapine.
Method
In this paper, we report on four cases in which adjunctive therapy with aripiprazole was tested to alleviate obsessive-compulsive symptoms in schizophrenia.
Results
All four patients had a significant improvement in obsessive-compulsive symptoms. The combination of clozapine and aripiprazole was well tolerated.
Conclusion
This case series demonstrates the clinical efficacy of aripiprazole adjunctive therapy with clozapine in schizophrenic patients with comorbid obsessive-compulsive symptoms. Larger-sampled and controlled studies are …
学术搜索中的文章
G Eryılmaz, G Hızlı Sayar, E Ozten, I Gögcegöz Gül… - Annals of General Psychiatry, 2013